Assessment

• Patients who have asthma, aspirin-induced allergy, and nasal polyps are at increased risk for developing hypersensitivity reactions

• Assess pain and limitation of movement; note type, location, and intensity before and 30–60 min after administration

• Monitor blood pressure closely during initiation of treatment and periodically during therapy in patients with hypertension

• Diclofenac has minimal effect on bleeding time and platelet aggregation

» Monitor CBC and chemistry profile periodically during therapy. May cause anemia, liver or renal dysfunction

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