Davis's Drug Guide

doripenem

Pharmacokinetics

Absorption: IV administration results in complete bioavailability

Distribution: Penetrates renal and peritoneal and retroperitoneal tissues and fluids

Metabolism and Excretion: Mostly excreted unchanged in urine; minimal metabolism

Half-life: 1 hr

TIME/ACTION PROFILE (blood levels)

ROUTEONSETPEAKDURATION
IVunknownend of infusion8 hr*

*Normal renal function



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