Pharmacokinetics

Absorption: Complete after IV administration

Distribution: Unknown

Metabolism and Excretion: Inactivated by binding to plasmin inactivators

Half-life: 70–120 minutes

TIME/ACTION PROFILE (fibrinolysis)

ROUTE	ONSET	PEAK	DURATION
IV	unknown	45 min	6 hr†

†Systemic hyperfibrinolytic state may persist for up to 2 days

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