ursodiol

Route/Dosage

• PO (Adults): Gallstone dissolution—Initial 8–10 mg/kg/day in 2–3 divided doses; maintenance: 250 mg/day at bedtime for 6 mo–1 yr; Gallstone prevention—300 mg twice daily; Primary biliary cirrhosis—13–15 mg/kg/day in 2–4 divided doses..

• PO (Children and Infants): TPN-induced cholestasis—30 mg/kg/day in 2–3 divided doses..

• PO (Infants): Biliary atresia—10–15 mg/kg/day..