Davis's Drug Guide
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linagliptin

Pharmacokinetics

Absorption: 30% absorbed following oral administration.

Distribution: Extensively distributed to tissues.

Metabolism and Excretion: Approximately 90% excreted unchanged in urine; mininally metabolized.

Half-life: > 100 hr (due to saturable binding to DPP-4).

TIME/ACTION PROFILE

ROUTEONSETPEAKDURATION
POunknown1.5 hr†24 hr

† Blood level.

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