Davis's Drug Guide

Pediatric Intravenous Medication Quick Reference Chart

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General

PEDIATRIC INTRAVENOUS MEDICATION QUICK REFERENCE CHART

Risk of fluid overload in infants and children is always a consideration when administering IV medications. The following table provides maximum concentrations—the smallest amount of fluid necessary for diluting specific medications—and the maximum rate at which the medications be given.

Drug

Maximum Concentration

Maximum Rate

acetazolamide

100 mg/ml

500 mg/min2

acyclovir

10 mg/ml

Give over 1 hr

adenosine

3 mg/ml

Give over 1-2 sec

allopurinol

6 mg/ml

Give over 30 min

amikacin

10 mg/ml

Give over 30 min

aminocaproic acid

20 mg/ml

Give over 1 hr

aminophylline

25 mg/ml

25 mg/min

amphotericin B conventional

0.1 mg/ml (peripherally)

0.5 mg/ml (centrally)

Give over 2-6 hr

Give over 2-6 hr

amphotericin B liposomal

2 mg/ml

Give over 2 hr

amphotericin B colloidal

0.83 mg/ml

Give over 2 hr

ampicillin

100 mg/ml

100 mg/min

ampicillin/sulbactam

30 mg/ml (ampicillin)

Give over 15-30 min

anidulafungin

0.43 mg/ml

1.1 mg/min

atropine

1 mg/ml

Give over 1 min

azithromycin

2 mg/ml

Give over 1 hr

aztreonam

20 mg/ml

Give over 20-60 min

bumetanide

0.25 mg/ml

Give over 1-2 min

caffeine citrate

20 mg/ml

Give over 10-20 min

calcitriol

1 mcg/ml

Give over 15 sec

calcium chloride

100 mg/ml

100 mg/min

calcium gluconate

100 mg/ml

100 mg/min2

caspofungin

0.5 mg/ml

Give over 1 hr

cefazolin

138 mg/ml (IVP)

20 mg/ml (Intermittent infusion)

Give over 3-5 min

Give over 10-60 min

cefepime

100 mg/ml

Give over 30 min

cefotaxime

150 mg/ml (IVP)

60 mg/ml (Intermittent infusion)

Give over 3-5 min

Give over 10-30 min

cefoxitin

200 mg/ml (IVP)

40 mg/ml (Intermittent infusion)

Give over 3-5 min

Give over 10-60 min

ceftazidime

180 mg/ml (IVP)

40 mg/ml (Intermittent infusion)

Give over 3-5 min

Give over 10-30 min

ceftriaxone

40 mg/ml

Give over 10-30 min

cefuroxime

100 mg/ml (IVP)

137 mg/ml (Intermittent infusion)2

Give over 3-5 min

Give over 15-30 min

chlorpromazine

1 mg/ml

0.5 mg/min

ciprofloxacin

2 mg/ml

Give over 60 min

clindamycin

18 mg/ml

30 mg/min

cyclosporine

2.5 mg/ml

Give over 2-6 hr

dexamethasone

10 mg/ml

Doses < 10 mg:

Give over 1-4 min

Doses > 10 mg:

Give over 15-30 min

diazepam

5 mg/ml

2 mg/min

digoxin

100 mcg/ml

Give over 5 min

diphenhydramine

50 mg/ml

25 mg/min

doxycycline

1 mg/ml

Give over 1 hr

enalaprilat

1.25 mg/ml

Give over 5 min

erythromycin

5 mg/ml

Give over 20-120 min

ethacrynic acid

2 mg/ml

Give over 5-30 min

famotidine

4 mg/ml (IVP)

0.2 mg/ml (Intermittent infusion)

10 mg/min

Give over 15-30 min

fentanyl

50 mcg/ml

Give over 1-3 min

fluconazole

2 mg/ml

Give over 1-2 hr

flumazenil

0.1 mg/ml

0.2 mg/min

foscarnet

12 mg/ml (peripherally)

24 mg/ml (centrally)

60 mg/kg/hr

fosphenytoin

25 mg/ml

3 mg/kg/min

furosemide

10 mg/ml

0.5 mg/kg/min

ganciclovir

10 mg/ml

Give over 1 hr

gentamicin

10 mg/ml

Give over 30 min

glycopyrrolate

0.2 mg/ml

20 mcg/min

granisetron

50 mcg/ml (Intermittent infusion)

1 mg/ml (IVP)

Give over 2-30 min

Give over 30 sec

hydralazine

20 mg/ml

0.2 mg/kg/min

hydrocortisone sodium

succinate

50 mg/ml (IVP)

5 mg/ml (Intermittent infusion)

Give over 30 sec

Give over 10-30 min

PEDIATRIC INTRAVENOUS MEDICATION QUICK REFERENCE CHART (continued)

Risk of fluid overload in infants and children is always a consideration when administering IV medications. The following table provides maximum concentrations—the smallest amount of fluid necessary for diluting specific medications—and the maximum rate at which the medications be given.

Drug

Maximum Concentration

Maximum Rate

imipenem/cilastatin2

7 mg/ml

Give over 15-60 min

inamrinone

5 mg/ml

Give over 2-3 min

indomethacin

1 mg/ml

Give over 20-35 min

kanamycin

5 mg/ml

Give over 20-30 min

ketamine

50 mg/ml (IVP)

2 mg/ml (Intermittent infusion)

0.5 mg/kg/min

0.5 mg/kg/min

ketorolac

30 mg/ml

Give over 1-5 min

labetalol

5 mg/ml (IVP)

2 mg/min

lansoprazole

0.12 mg/ml

Give over 30 min

levocarnitine

200 mg/ml

Give over 2-3 min

levothyroxine

100 mcg/ml

Give over 2-3 min

linezolid

2 mg/ml

Give over 30-120 min

lorazepam

4 mg/ml

2 mg/min or 0.05 mg/kg

over 2-5 min

magnesium sulfate

200 mg/ml

10-20 min

meperidine2

10 mg/ml

Give over 5 min

meropenem

50 mg/ml (IVP)

20 mg/ml (Intermittent infusion)

Give over 3-5 min

Give over 15-30 min

methylprednisolone

125 mg/ml (IVP)

2.5 mg/ml (Intermittent infusion)

Give over 1-30 min

Give over 20-60 min

metoclopramide

5 mg/ml

5 mg/min

metronidazole

8 mg/ml

Give over 1 hr

micafungin

1.5 mg/ml

Give over 1 hr

midazolam

5 mg/ml

Give over 20-30 sec

(5 min in neonates)

milrinone

1 mg/ml

Give over 10 min

morphine2

5 mg/ml

Give over 5-30 min

nafcillin2

100 mg/ml

Give over 15-60 min

naloxone

1 mg/ml

Give over 30 sec

ondansetron

2 mg/ml

Give over 2-15 min

oxacillin

100 mg/ml (IVP)

40 mg/ml (Intermittent infusion)

Give over 10 min

Give over 15-30 min

pancuronium

2 mg/ml (IVP)

Give over 3-5 seconds

pantoprazole

4 mg/ml

Give over 2-15 min

penicillin g2

50,000 units/ml (neonates/infants)

500,000 units/ml (children)

Give over 15-30 min

Give over 15-60 min

pentamidine

6 mg/ml

Give over 1-2 hr

pentobarbital

50 mg/ml

50 mg/min

phenobarbital

130 mg/ml

30 mg/min

phenytoin

10 mg/ml

1 mg/kg/min (neonates)

3 mg/kg/min (children)

phytonadione

10 mg/ml

1 mg/min

piperacillin

200 mg/ml (IVP)

20 mg/ml (Intermittent infusion)

Give over 3-5 min

Give over 20-60 min

piperacillin/tazobactam

200 mg/ml

Give over 30 min

potassium chloride

80 mEq/L (peripherally)

200 mEq/L (centrally)

1 mEq/kg/hr

promethazine

25 mg/ml

25 mg/min

propranolol

1 mg/ml

1 mg/min

protamine

10 mg/ml

5 mg/min

ranitidine

2.5 mg/ml

10 mg/min

rifampin

6 mg/ml

Give over 30 min

tacrolimus

0.02 mg/ml

Give over 4-24 hr

terbutaline

1 mg/ml

Give over 5-10 min

ticarcillin/clavulanate

100 mg/ml

Give over 10-60 min

tobramycin

10 mg/ml

Give over 30 min

trimethoprim/sulfamethoxazole

1 ml drug per 10 ml diluent2

Give over 1-1.5 hr

valproate sodium

50 mg/ml

3 mg/kg/min

vancomycin

5 mg/ml

Give over 60 min

vasopressin

1 unit/ml

Give over 5-30 min

verapamil

2.5 mg/ml (IVP)

Give over 2-3 min

voriconazole

5 mg/ml

3 mg/kg/hr

zidovudine

4 mg/ml

Give over 60 min

  1. Phelps SJ, Hak EB, Crill CM: Pediatric Injectable Drugs, 8th Edition. American Society of Health-System Pharmacists, Bethesda, MD 2007.
  2. Taketomo CK, Hodding JH, Kraus DM: Pediatric Dosage Handbook, 18th Edition. Lexi-Comp, Hudson, OH 2011-12

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