Davis's Drug Guide

acetaZOLAMIDE

Assessment

• Observe for signs of hypokalemia (muscle weakness, malaise, fatigue, ECG changes, vomiting)

» Assess for allergy to sulfonamides



Intraocular Pressure

• Assess for eye discomfort or decrease in visual acuity



Seizures

• Monitor neurologic status in patients receiving acetazolamide for seizures. Initiate seizure precautions



Altitude Sickness

• Monitor for decrease in severity of symptoms (headache, nausea, vomiting, fatigue, dizziness, drowsiness, shortness of breath). Notify health care professional immediately if neurologic symptoms worsen or if patient becomes more dyspneic and rales or crackles develop



Lab Test Considerations

• Serum electrolytes, complete blood counts, and platelet counts should be evaluated initially and periodically throughout prolonged therapy. May cause potassium, bicarbonate, WBCs, and RBCs. May cause serum chloride

» May cause in serum and urine glucose; monitor serum and urine glucose carefully in diabetic patients

» May cause false-positive results for urine protein and 17-hydroxysteroid tests

» May cause blood ammonia, bilirubin, uric acid, urine urobilinogen, and calcium. May urine citrate



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