Assessment

• Observe patient for signs and symptoms of hypoglycemic reactions (sweating, hunger, weakness, dizziness, tremor, tachycardia, anxiety)

• Assess patient for allergy to sulfonamides

• Serum glucose and Hb A_1c should be monitored periodically throughout therapy to evaluate effectiveness of treatment

» Monitor CBC periodically throughout therapy. Notify physician or other health care professional promptly if decrease in blood counts occurs

» May cause an increase in AST, LDH, BUN, and serum creatinine

• Overdose is manifested by symptoms of hypoglycemia. Mild hypoglycemia may be treated with administration of oral glucose. Severe hypoglycemia should be treated with IV D50W followed by continuous IV infusion of more dilute dextrose solution at a rate sufficient to keep serum glucose at approximately 100 mg/dl

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