Patient/Family Teaching

• Instruct patient to take medication exactly as directed

• Inform patient that mild headache may occur during first 48 hr of treatment. Headaches usually respond to oral salicylates (aspirin) and usually disappear spontaneously

• Advise patient that taking acetohydroxamic acid concurrently with alcohol may cause a nonpruritic macular skin rash to occur on upper extremities and face. Rash usually appears 30–45 min after ingestion of alcohol and may be associated with a sensation of warmth. It usually spontaneously disappears in 30–60 min

• Emphasize the importance of periodic lab tests to monitor for side effects

• Caution patients of childbearing potential to use a reliable form of contraception while taking acetohydroxamic acid

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