Route/Dosage

• PO (Adults): 250 mg 3–4 times daily (total dose 10–15 mg/kg/day)(maximum daily dose = 1500 mg).

• PO (Children): 10 mg/kg/day in divided doses; further titration may be necessary.

• PO (Adults):
Serum creatinine 1.8–2.5 mg/dl—do not exceed 1000 mg/day (given at 12 hr intervals; further adjustments may be necessary).

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