Interactions

Drug-Drug

• Probenecid blood levels of acyclovir

• blood levels and risk of toxicity from theophylline; dose adjustment may be necessary

• blood levels and may effectiveness of valproic acid or hydantoins

• Concurrent use of other nephrotoxic drugs risk of adverse renal effects

• Zidovudine and IT methotrexate may risk of CNS side effects

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