Davis's Drug Guide

alemtuzumab

Pharmacokinetics

Absorption: IV administration results in complete bioavailability

Distribution: Binds to CD52 receptors

Metabolism and Excretion: Unknown

Half-life: 12 days

TIME/ACTION PROFILE (hematologic parameters)

ROUTEONSETPEAKDURATION
IVunknown2–4 mos‡7–11 mos‡‡

‡Median time to response
‡‡Duration of response



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