Contraindication/Precautions

Contraindicated in:

• Renal insufficiency (CCr <35 ml/min)

• OB: Lactation: Safety not established

• Patients with active GI pathology (dysphagia, esophageal disease, gastritis, duodenitis, ulcers)

• Pre-existing hypocalcemia or vitamin D deficiency

• Concurrent dental surgery (may risk of jaw osteonecrosis)

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