Implementation

• Do not confuse Xanax (alprazolam) with Zantac (ranitidine)

» If early morning anxiety or anxiety between doses occurs, the same total daily dose should be divided into more frequent intervals

• PO: May be administered with food if GI upset occurs. Administer greatest dose at bedtime to avoid daytime sedation

» Tablets may be crushed and taken with food or fluids if patient has difficulty swallowing. Do not crush, break, or chew extended-release tablets

» Taper by 0.5 mg q 3 days to prevent withdrawal. Some patients may require longer tapering period (months)

» For orally disintegrating tablets: Remove tablet from bottle with dry hands just prior to taking medication. Place tablet on tongue. Tablet will dissolve with saliva; may also be taken with water. Remove cotton from bottle and reseal tightly to prevent moisture from entering bottle. If only ½ tablet taken, discard unused portion immediately; may not remain stable

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