Pharmacokinetics
Absorption: Action is primarily local following intracavernosal injection; after intraurethral use, it is absorbed into the corpora cavernosa
Distribution: Unknown
Metabolism and Excretion: Mostly metabolized locally; any systemically absorbed alprostadil is metabolized in the liver
Half-life: 5–10 min
TIME/ACTION PROFILE (erection)
| ROUTE | ONSET | PEAK | DURATION |
| Intracavernosal | 5–10 min | within 20 min | 1 hr |
| Intraurethral | 5–10 min | within 20 min | 0.5–1 hr |
alprostadil (intracavernosal, intraurethral) is a sample topic found in Davis's Drug Guide. All other sections of this record are viewable by clicking on the index in the left column, or by clicking on "Display all Sections" in the "Content Manager".
To find other Davis's Drug Guide topics, please login or purchase a subscription.
Davis's Drug Guide
