Davis's Drug Guide

amantadine

Pharmacokinetics

Absorption: Well absorbed from the GI tract

Distribution: Distributed to various body tissues and fluids. Crosses blood-brain barrier and enters breast milk

Metabolism and Excretion: Excreted unchanged in the urine

Half-life: 10–28 hr

TIME/ACTION PROFILE (antiparkinson effect)

ROUTEONSETPEAKDURATION
POwithin 48 hrup to 2 wkunknown



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