Davis's Drug Guide

amifostine

Contraindication/Precautions

Contraindicated in:

• Known sensitivity to aminothiol compounds

• Hypotension or dehydration

Lactation: Use an alternative to breast milk

• Concurrent antineoplastic therapy for other tumors (especially malignancies of germ cell origin)



Use Cautiously in:

OB: Safety not established

Geri: Geriatric patients or patients with cardiovascular disease have increased risk of adverse reactions



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