Davis's Drug Guide

amifostine

Route/Dosage

Reduction of Renal Damage with Cisplatin

IV (Adults): 910 mg/m² once daily, within 30 min before chemotherapy; if full dose is poorly tolerated, subsequent doses should be decreased to 740 mg/m².



Reduction of Xerostomia from Radiation

IV (Adults): 200 mg/m² once daily, as a 3-minute infusion starting 15–30 min before standard fraction radiation therapy.



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