Implementation

• Do not confuse Amicar (aminocaproic acid) with Amikin (amikacin)

• PO: Syrup may be used as an oral rinse, swished for 30 sec 4 times/day for 7–10 days for the control of bleeding during dental and oral surgery in hemophilic patients. Small amounts may be swallowed, except during 1st and 2nd trimesters of pregnancy. Syrup may be applied with an applicator in children or unconscious patients

• IV:
Stabilize IV catheter to minimize thrombophlebitis. Monitor site closely

• Intermittent Infusion:
Diluent: Do not administer undiluted. Dilute initial 4–5 g dose in 250 ml of sterile water for injection, 0.9% NaCl, D5W, or LR. Do not dilute with sterile water in patients with subarachnoid hemorrhage.
Concentration: 20 mg/ml

• Rate:
Single doses: Administer over 1 hr. Rapid infusion rate may cause hypotension, bradycardia, or other arrhythmias

• Continuous Infusion:
Administer IV solution using infusion pump to ensure accurate dose. Administer via slow IV infusion

• Rate:
Initial dose may be followed by a continuous infusion of 1–1.25 g/hr in adults or 33.3 mg/kg/hr in children

• Additive Incompatibility:
Do not admix with other medications

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