Interactions

Drug-Drug

• Induces (stimulates) hepatic P450 microsomal enzymes, which are responsible for metabolizing many drugs

• Increases metabolism and decreases effectiveness of dexamethasone

• May decrease the effects of warfarin, theophylline, megestrol tamoxifen, and medroxyprogesterone

• Alcohol potentiates the effects of aminoglutethimide

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