Route/Dosage

Cushing's Disease

• PO (Adults): 250 mg q 6 hr; may be increased in increments of 250 mg daily at 1–2 wk intervals (maximum daily dose should not exceed 2000 mg).

• PO (Adults): 250 mg twice daily for 2 wk (up to 2 g/day; with hydrocortisone) followed by increases to 250 mg qid.

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