Davis's Drug Guide

amiodarone

Contraindication/Precautions

Contraindicated in:

• Patients with cardiogenic shock

• Severe sinus node dysfunction

• 2nd- and 3rd-degree AV block

• Bradycardia (has caused syncope unless a pacemaker is in place)

• Hypersensitivity to amiodarone or iodine

OB: Can cause fetal hypo- or hyperthyroidism

Lactation: Enters breast milk and can cause harm to the neonate; use an alternative to breast milk

Pedi: Safety not established; products containing benzyl alcohol should not be used in neonates



Use Cautiously in:

• History of CHF

• Thyroid disorders

• Corneal refractive laser surgery

• Severe pulmonary or liver disease

Geri: Appears on Beers list. Potential to affect QT interval and cause torsades de pointes. Initiate therapy at the low end of the dosing range due to decreased hepatic, renal, or cardiac function; comorbid disease; or other drug therapy



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