Interactions

Drug-Drug

• Probenecid ↓ renal excretion and ↑ blood levels of amoxicillin—therapy may be combined for this purpose

• May ↑ the effect of warfarin

• Concurrent allopurinol therapy ↑ risk of rash

• May ↓ the effectiveness of hormonal contraceptives

Drug-Food
Clavulanate absorption is ↓ by a high fat meal

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