Route/Dosage

• Dose is expressed in total amphetamine content (amphetamine + dextroamphetamine)

• PO (Adults and Children >= 12 yr): 10–60 mg/day in divided doses; start with 10 mg/day, increase by 10 mg/day at weekly intervals. Sustained-release capsules can be given once daily, tablets every 8–12 hr.

• PO (Children 6–12 yr): 5 mg once daily; may increase by 5 mg/day at weekly intervals to a maximum of 60 mg/day.

• PO (Children >=6 yr): 5 mg/day 1–2 times daily; increase daily dose by 5 mg at weekly intervals. Sustained-release capsules can be given once daily, tablets every 8–12 hr. If starting therapy with extended release capsules, start with 10 mg once daily and increase by 10 mg/day at weekly intervals (up to 40 mg/day).

• PO (Adults): 20 mg/day initially (as extended-release product).

• PO (Children 3–5 yr): 2.5 mg/day in the morning; increase daily dose by 2.5 mg at weekly intervals not to exceed 40 mg/day.

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