Davis's Drug Guide

amprenavir

Pharmacokinetics

Absorption: Rapidly absorbed after oral administration

Distribution: 90%; bound to plasma proteins

Metabolism and Excretion: Mostly metabolized by the liver; <3% excreted unchanged by the kidneys

Half-life: 7.1–10.6 hr

TIME/ACTION PROFILE (blood levels)

ROUTEONSETPEAKDURATION
POrapid 1–2 hr8–12 hr



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