Hypersensitivity to other Escherichia coli derived products.Use Cautiously in:
Other chronic debilitating illness;
OB: Lactation: Pedi: Safety not established;
Geri: May be more sensitive to toxicity due to age-related decline in renal function; increased incidence of infection in geriatric population.Exercise Extreme Caution in:
Concurrent use of TNF blocking agents such as etanercept (higher risk of serious infections).