Davis's Drug Guide

bumetanide

Interactions

Drug-Drug

• ↑ hypotension with antihypertensives , nitrates , or acute ingestion of alcohol

• ↑ risk of hypokalemia with other diuretics , amphotericin B , stimulant laxatives , and corticosteroids

• Hypokalemia may ↑ risk of digoxin toxicity and ↑ risk of arrhythmia in patients taking drugs that prolong the QT interval

• ↓ lithium excretion, may cause lithium toxicity

• ↑ risk of ototoxicity with aminoglycosides

• NSAIDS ↓ effects of bumetanide



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