Davis's Drug Guide

chlorambucil

Interactions

Drug-Drug

• Additive bone marrow depression with other bone marrow depressants (antineoplastics) or immunosuppressant agents

• May decrease antibody response to live-virus vaccines and increase the risk of adverse reactions



Drug-Natural Products
Concommitant use with astragalus, echinacea, and melatonin may interfere with immunosuppression



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