Implementation

• Medication should be administered around the clock

• Direct IV: Reconstitute to a 10% solution by adding 10 ml of sterile water for injection or D5W to each 1 g for a concentration of not greater than 100 mg/ml. Do not use preparations containing benzyl alcohol in neonates

• Rate: Inject slowly over at least 1 min

• Intermittent Infusion: May be further diluted in 50–100 ml of D5W, D10W, D5/0.9% NaCl, D5/0.45% NaCl, D5/0.225% NaCl, D5/LR, 0.45% NaCl, 0.9% NaCl, or LR. Solution may form crystals at low temperatures. Shake well to dissolve crystals. Do not administer cloudy solutions

• Rate: Administer over 30–60 min

• Y-Site Compatibility:

» acyclovir

» cyclophosphamide

» enalaprilat

» esmolol

» foscarnet

» hydromorphone

» labetalol

» magnesium sulfate

» meperidine

» morphine

» perphenazine

» tacrolimus

• Y-Site Incompatibility:

» fluconazole

chloramphenicol is a sample topic found in Davis's Drug Guide. All other sections of this record are viewable by clicking on the index in the left column, or by clicking on "Display all Sections" in the "Content Manager".

To find other Davis's Drug Guide topics, please login or purchase a subscription.