Pharmacokinetics
Absorption: Well absorbed from the GI tract. IM absorption may be slow and unpredictable
Distribution: Widely distributed. Crosses the blood-brain barrier. Crosses the placenta; enters breast milk. Recommend to discontinue drug or bottle feed
Metabolism and Excretion: Highly metabolized by the liver. Some products of metabolism are active as CNS depressants
Half-life: 5–30 hr
TIME/ACTION PROFILE (sedation)
| ROUTE | ONSET | PEAK | DURATION |
| PO | 1–2 hr | 0.5–4 hr | up to 24 hr |
| IM | 15–30 min | unknown | unknown |
| IV | 1–5 min | unknown | 0.25–1 hr |
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