Interactions
Drug-Drug
Alcohol, antidepressants, antihistamines, and opioid analgesics concurrent use results in additive CNS depression
Cimetidine, oral contraceptives , disulfiram, fluoxetine, isoniazid, ketoconazole, metoprolol, propoxyphene, propranolol, or valproic acid may enhance effects
May
efficacy of levodopa
Rifampin or barbiturates may
effectiveness of chlordiazepoxide
Sedative effects may be
by theophylline
Drug-Natural Products Concomitant use of
kava,
valerian,
chamomile, or
hops can

CNS depression
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