Interactions

Drug-Drug

• ↑ CNS depression with other CNS depressants , including alcohol , opioid analgesics , and sedative/hypnotics

• MAO inhibitors intensify and prolong anticholinergic effects of antihistamines

• ↑ anticholinergic effects with other drugs possessing anticholinergic properties , including antidepressants , atropine , haloperidol , phenothiazines , quinidine , and disopyramide

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