Contraindication/Precautions

Contraindicated in:

• Hypersensitivity

• Hypersensitivity to sulfites (injectable) or benzyl alcohol (sustained-release capsules)

• Cross-sensitivity with other phenothiazines may occur

• Angle-closure glaucoma

• Bone marrow depression

• Severe liver/cardiovascular disease

• Concurrent pimozide use

• Geriatric/debilitated patients ( initial dose)

• Diabetes

• Respiratory disease

• Prostatic hyperplasia

• CNS tumors

• Epilepsy

• Intestinal obstruction

• OB: Lactation: Safety not established. Discontinue drug or bottle feed.

• Pedi: Children with acute illnesses, infections, gastroenteritis, or dehydration (increased risk of extrapyramidal reactions)

• Geri: risk of mortality in elderly patients treated for dementia-related psychosis

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