Pharmacokinetics

Absorption: Well absorbed after oral administration

Distribution: 0.13–0.23 L/kg; enters breast milk

Metabolism and Excretion: Mostly metabolized by the liver; 10–30% excreted in urine as unchanged drug

Protein Binding: 60–90%

Half-life: 36 hr

TIME/ACTION PROFILE (hypoglycemic activity)

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