Contraindication/Precautions

Contraindicated in:

• Hypersensitivity

• Cross-sensitivity with sulfonamides (including thiazide diuretics) may occur

• Type 1 diabetics

• Diabetic coma or ketoacidosis

• Severe renal or hepatic disease

• Uncontrolled infection, serious burns, or trauma

• Lactation: Discontinue or bottle feed

• Severe cardiovascular disease

• Hepatic or renal impairment (increased risk of hypoglycemia)

• Infection, stress, or changes in diet may alter requirements for control of blood sugar

• Impaired thyroid, pituitary, or adrenal function

• Malnutrition, high fever, prolonged nausea, or vomiting

• OB: Safety not established; insulin recommended during pregnancy

• Geri: Prolonged half-life in geriatric patients may cause hypoglycemia, dosage reduction may be required. Appears on Beers list.

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