Pharmacokinetics

Absorption: IV administration results in complete bioavailability

Distribution: Extensively distributed to body tissues; penetrates into cerebrospinal fluid

Metabolism and Excretion: Unknown

Half-life: 3–22 hr

TIME/ACTION PROFILE (noted as effect on peripheral counts)

ROUTE	ONSET	PEAK	DURATION†
Platelets	unknown	unknown	12 days
Absolute neutrophil count	unknown	unknown	5 wk
Hemoglobin	unknown	unknown	8 wk

†Time to normalization of counts

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