Patient/Family Teaching

• Instruct patient to take clomiphene exactly as directed at the same time each day. Missed doses should be taken as soon as remembered and the dose doubled if not remembered until the time of the next dose. Notify health care professional if more than one dose is missed

• Advise patient that conception should be attempted with intercourse every other day starting 48 hr prior to ovulation. Ovulation usually occurs 7 days (range 5–10) after last dose of clomiphene

• Instruct patient in the correct method for measuring basal body temperature. A record of the daily basal body temperature should be maintained prior to and throughout course of therapy. Emphasize the importance of compliance with all aspects of therapy

• Prior to therapy, patient should be informed of the potential for multiple births

• Medication may cause visual disturbances or dizziness. Caution patient to avoid driving until the response to the medication is known

• Instruct patient to notify health care professional immediately if pregnancy is suspected; clomiphene should not be taken during pregnancy

• Advise patient that ophthalmologic exams should be performed to evaluate the possibility of ocular toxicity if treatment is continued for more than 1 yr

• Advise patient to notify health care professional promptly if bloating, stomach or pelvic pain, blurred vision, jaundice, persistent hot flashes, breast discomfort, headache, diarrhea, weight gain, or nausea and vomiting occur

• Emphasize the importance of close monitoring by health care professional throughout therapy

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