Route/Dosage

• PO (Adults):
Antiobsessive—25 mg/day, increased over 2-wk period to 100 mg/day in divided doses. May be further increased over several weeks up to 250–300 mg/day in divided doses. Once stabilizing dose is reached, entire daily dose may be given at bedtime.
Antidepressant—25 mg 3 times daily, may be increased as needed (unlabeled).

• PO (Geriatric Patients): 20–30 mg/day initially, may be increased as needed.

• PO (Children >10–17 yr): 25 mg/day initially, increased over 2-wk period to 3 mg/kg/day or 100 mg/day (whichever is smaller) in divided doses. May be further increased to 3 mg/kg/day or 200 mg/day (whichever is smaller) in divided doses. Once stabilizing dose is reached, entire daily dose may be given at bedtime.

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