Implementation

• Do not confuse clonazepam with clonidine or clorazepate

» Institute seizure precautions for patients on initial therapy or undergoing dose manipulations

• PO: Administer with food to minimize gastric irritation. Tablets may be crushed if patient has difficulty swallowing. Administer largest dose at bedtime to avoid daytime sedation. Taper by 0.25 mg every 3 days to decrease signs and symptoms of withdrawal. Some patients may require longer taper period (months)

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