Implementation

• Do not confuse Catapres (clonidine) with Cataflam (diclofenac)

» Do not confuse clonidine with clonazepam (Klonopin)

» In the perioperative setting, continue clonidine up to 4 hr prior to surgery and resume as soon as possible thereafter. Do not interrupt transdermal clonidine during surgery. Monitor blood pressure carefully

• PO: Administer last dose of the day at bedtime

• A 0.1 mg/mL oral suspension may be compounded for pediatric patients

• Transdermal: Transdermal system should be applied once every 7 days. May be applied to any hairless site; avoid cuts or calluses. Absorption is greater when placed on chest or upper arm and decreased when placed on thigh. Rotate sites. Wash area with soap and water; dry thoroughly before application. Apply firm pressure over patch to ensure contact with skin, especially around edges. Remove old system and discard. System includes a protective adhesive overlay to be applied over medication patch to ensure adhesion, should medication patch loosen

• Epidural: Dilute 500 mcg/mL with 0.9% NaCl for a concentration of 100 mcg/mL. Do not administer solutions that are discolored or contain a precipitate. Discard unused portion

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