Davis's Drug Guide

diazepam

Route/Dosage

Antianxiety

PO (Adults): 2–10 mg 2–4 times daily.

IM, IV (Adults): 2–10 mg, may repeat in 3–4 hr as needed.

PO (Children >6 mo): 1–2.5 mg 3–4 times daily.

IM, IV (Children >1 mo): 0.04–0.3 mg/kg/dose q 2–4 hr to a maximum of 0.6 mg/kg within an 8 hr period if necessary.

Precardioversion

IV (Adults): 5–15 mg 5–10 min precardioversion.

Pre-endoscopy

IV (Adults): 2.5–20 mg.

IM (Adults): 5–10 mg 30 min pre-endoscopy.

Pediatric Conscious Sedation for Procedures

PO (Children >6 mo): 0.2–0.3 mg/kg (not to exceed 10 mg/dose) 45–60 min prior to procedure.

Status Epilepticus/Acute Seizure Activity

IV (Adults): 5–10 mg, may repeat q 10–15 min to a total of 30 mg, may repeat regimen again in 2–4 hr (IM route may be used if IV route unavailable); larger doses may be required.

IM, IV (Children B5 yr): 0.05–0.3 mg/kg/dose given over 3–5 min q 15–30 min to a total dose of 10 mg, repeat q 2–4 hr.

IM, IV (Children 1 mo–5 yr ): 0.05–0.3 mg/kg/dose given over 3–5 min q 15–30 min to maximum dose of 5 mg, repeat in 2–4 hr if needed.

IV (Neonates): 0.1–0.3 mg/kg/dose given over 3–5 min q 15–30 min to maximum dose of 2 mg.

Rect (Adults and Children >12 yr): 0.2 mg/kg; may repeat 4–12 hr later.

Rect (Children 6–11 yr): 0.3 mg/kg; may repeat 4–12 hr later.

Rect (Children 2–5 yr): 0.5 mg/kg; may repeat 4–12 hr later.

Febrile Seizure Prophylaxis

PO (Children >1 mo): 1 mg/kg/day divided q 8 hr at first sign of fever and continue for 24 hr after fever is gone.

Skeletal Muscle Relaxation

PO (Adults): 2–10 mg 3–4 times daily.

PO (Geriatric Patients or Debilitated Patients): 2–2.5 mg 1–2 times daily initially.

PO (Children >6 mo): 1–2.5 mg 3–4 times daily.

IM, IV (Adults): 5–10 mg; may repeat in 2–4 hr (larger doses may be required for tetanus).

IM, IV (Geriatric Patients or Debilitated Patients): 2–5 mg; may repeat in 2–4 hr (larger doses may be required for tetanus).

IM, IV (Children B5 yr): Tetanus—5–10 mg q 3–4 hr.

IM, IV (Children >1 mo): Tetanus—1–2 mg q 3–4 hr.

Alcohol Withdrawal

PO (Adults): 10 mg 3–4 times in first 24 hr, decrease to 5 mg 3–4 times daily.

IM, IV (Adults): 10 mg initially, then 5–10 mg in 3–4 hr as needed; larger or more frequent doses have been used.

Psychoneurotic Reactions

IM, IV (Adults): 2–10 mg, may be repeated in 3–4 hr.



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