Interactions

Primarily noted for oral administration

Drug-Drug

• adverse GI effects with aspirin, other NSAIDs, or corticosteroids

• May effectiveness of diuretics, or antihypertensives

• May levels/risk of toxicity from cyclosporine, lithium, or methotrexate

• risk of bleeding with some cephalosporins, thrombolytic agents, antiplatelet agents, or warfarin

• Concurrent use of oral NSAIDs during topical diclofenac therapy should be minimized

Drug-Natural Products
bleeding risk with arnica, chamomile, clove, dong quai, feverfew, garlic, ginger, ginkgo, Panax ginseng, and others

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