Assessment

• Patients who have asthma, aspirin-induced allergy, and nasal polyps are at risk for developing hypersensitivity reactions

• Assess pain and limitation of movement; note type, location, and intensity before and 30–60 min after administration

• Assess arthritic pain (note type, location, intensity) and limitation of movement before and periodically during therapy

• Assess lesions prior to and periodically during therapy

• Diclofenac has minimal effect on bleeding time and platelet aggregation

» May cause in hemoglobin and hematocrit

» Monitor liver function tests within 8 wk of initiating diclofenac therapy and periodically during therapy. May cause serum alkaline phosphatase, LDH, AST, and ALT concentrations

» Monitor BUN and serum creatinine periodically during therapy. May cause BUN and serum creatinine

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