Davis's Drug Guide

dimenhyDRINATE

Pharmacokinetics

Absorption: Well absorbed after oral or IM administration

Distribution: Probably crosses the placenta and enters breast milk

Metabolism and Excretion: Metabolized by the liver

Half-life: Unknown

TIME/ACTION PROFILE (anti–motion sickness, antiemetic activity)

ROUTEONSETPEAKDURATION
PO15–60 min1–2 hr3–6 hr
Rect 30–45 minunknown 6–12 hr
IM20–30 min1–2 hr3–6 hr
IVrapidunknown3–6 hr



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