Davis's Drug Guide
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dinoprostone

Pharmacokinetics

Absorption: Rapidly absorbed.

Distribution: Unknown. Action is mostly local.

Metabolism and Excretion: Metabolized by enzymes in lung, kidneys, spleen, and liver tissue.

Half-life: Unknown.

TIME/ACTION PROFILE

ROUTEONSETPEAKDURATION
Cervical ripening (gel)rapid30–45 minunknown
Cervical ripening (insert)rapidunknown12 hr
Abortion time (suppository)10 min12–24 hr2–3 hr

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Last updated: December 14, 2012
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