Davis's Drug Guide

diphenhydrAMINE

Action

• Antagonizes the effects of histamine at H1-receptor sites; does not bind to or inactivate histamine

• Significant CNS depressant and anticholinergic properties



Therapeutic Effect(s):

• Decreased symptoms of histamine excess (sneezing, rhinorrhea, nasal and ocular pruritus, ocular tearing and redness, urticaria)

• Relief of acute dystonic reactions

• Prevention of motion sickness

• Suppression of cough



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