Implementation

IV Adminstration:

• Direct IV:
Diluent: Administer undiluted.
Concentration: 2.5 mg/ml

• Rate:
Administer each dose slowly over 30–60 sec

• Intermittent Infusion:
Diluent: May be added to D5W, 0.9% NaCl, or LR.

• Rate:
Administer by slow IV infusion. Titrate according to patient response

• Syringe Compatibility:

» atropine

» bleomycin

» butorphanol

» chlorpromazine

» cimetidine

» cisplatin

» cyclophosphamide

» dimenhydrinate

» diphenhydramine

» doxorubicin

» fentanyl

» glycopyrrolate

» hydroxyzine

» meperidine

» metoclopramide

» midazolam

» mitomycin

» morphine

» nalbuphine

» pentazocine

» perphenazine

» prochlorperazine

» promethazine

» scopolamine

» vinblastine

» vincristine

• Syringe Incompatibility:

» fluorouracil

» furosemide

» heparin

» leucovorin calcium

» methotrexate

» ondansetron

» pentobarbital

• Y-Site Compatibility:

» amifostine

» azithromycin

» aztreonam

» bivalirudin

» bleomycin

» buprenorphine

» cisatracurium

» cladribine

» cisplatin

» cyclophosphamide

» cytarabine

» dexmedetomidine

» docetaxel

» doxorubicin

» doxorubicin liposome

» etoposide

» famotidine

» fenoldopam

» filgrastim

» fluconazole

» fludarabine

» gemcitabine

» granisetron

» hydrocortisone sodium succinate

» idarubicin

» linezolid

» melphalan

» meperidine

» metoclopramide

» mitomycin

» ondansetron

» oxaliplatin

» paclitaxel

» potassium chloride

» propofol

» remifentanil

» sargramostim

» teniposide

» thiotepa

» vinblastine

» vincristine

» vinorelbine

» vitamin B complex with C

• Y-Site Incompatibility:

» allopurinol sodium

» amphotericin B cholesteryl sulfate complex

» cefepime

» fluorouracil

» foscarnet

» furosemide

» lansoprazole

» leucovorin calcium

» nafcillin

» pemetrexed

» piperacillin/tazobactam

• Additive Incompatibility:

» barbiturates

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