Interactions

Drug-Drug

• Action may be antagonized by drugs possessing anticholinergic properties , including antihistamines , antidepressants , atropine , haloperidol , phenothiazines , quinidine , and disopyramide

• Prolongs action of depolarizing muscle-relaxing agents ( succinylcholine , decamethonium )

• May lead to ↑ bradycardia in patients receiving digoxin

Drug-Natural Products
Angel's trumpet , jimson weed , and scopolia may antagonize cholinergic effects

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