enoxaparin

Implementation

• Do not confuse Lovenox with Levemir.

• Cannot be used interchangeably (unit for unit) with unfractionated heparin or other low-molecular-weight heparins.

• SC: Administer deep into subcut tissue. Alternate injection sites daily between the left and right anterolateral and left and right posterolateral abdominal wall. Inject entire length of needle at a 45° or 90° angle into a skin fold held between thumb and forefinger; hold skin fold throughout injection. Do not aspirate or massage. Rotate sites frequently. Do not administer IM because of danger of hematoma formation. Solution should be clear, colorless to pale yellow; do not inject solution containing particulate matter.

» If excessive bruising occurs, ice-cube massage of site before injection may lessen bruising.

» To avoid the loss of drug, do not expel the air bubble from prefilled syringes before the injection. Use a tuberculin syringe when using multidose vials to ensure correct dose.

» To minimize risk of bleeding after vascular instrumentation for unstable angina, recommended intervals between doses should be followed closely. Leave vascular access sheath in place for 6–8 hr after enoxaparin dose. Give next enoxaparin dose ≥6–8 hr after sheath removal. Observe site for bleeding or hematoma formation.

• Direct IV:
(for treatment of STEMI only)Use multiple-dose vial. Inject via IV line. Flush with 0.9% NaCl or D5W prior to and following administration to avoid mixture with other drugs and clear the port of the drug. May be administered with 0.9% NaCl or D5W.

• Rate:
Inject as a bolus.

• Y-Site Incompatibility:
Do not mix or co-administered with other medications.