Pharmacokinetics
Absorption: ~100% absorbed after subcut administration.
Distribution: Unknown.
Metabolism and Excretion: Metabolized in the liver, primarily renally eliminated Clearance ↓ by 30% in renal impairment (CCr < 30 ml/min).
Half-life: Single dose: 4.5 hr; Repeat dosing: 7 hr.
TIME/ACTION PROFILE (anticoagulant effect)
| ROUTE | ONSET | PEAK | DURATION |
| Subcut | unknown | 3–5 hr | 12 hr |
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